Active Ingredient
Butylscopolaminiumbromide and Metamizole sodium (dipyrone).

Indication
For the management of abdominal pain associated with equine colic.

Characteristics
Buscopan® Compositum contains butylscopolaminiumbromide, an antispasmodic agent, and dipyrone, a non-steroidal anti-inflammatory drug (NSAID). Buscopan® Compositum does not mask the symptoms of surgical colic cases and does not produce paralysis of the gut.

Butylscopolaminiumbromide is a quaternary ammonium derivative of scopolamine. Like other belladonna alkaloid derivatives, this compound antagonises the actions of acetylcholine at the muscarinic receptor and also possesses some activity at nicotinic receptors.

Dipyrone shows anti-inflammatory, analgesic and antipyretic effects. Data indicate that the mechanism of action of dipyrone, like other NSAIDs, is probably associated with an inhibitory effect on prostaglandin synthesis. Furthermore, it antagonises the effects of bradykinin and histamine.

Application
single intravenous injection